The results of this study support the metabolic stabilizing effects of NMN in overweight or obese individuals.

According to a study conducted by Bhasin and Colleagues, the effects of NMN on weight were examined by administering two daily doses of 1,000mg of NMN to middle-aged and older adults who were overweight or obese for a period of 28 days. The results showed that participants who received NMN experienced a significant reduction in body weight, with a decrease of more than 7 pounds compared to those who did not receive NMN during the same period. This finding implies that NMN supplementation contributes to metabolic improvements, as demonstrated by the notable impact on body weight, which serves as a substantial indicator of metabolic health. 

In addition to investigating the impact of NMN on weight, the study also explored its effects on cardiovascular health, specifically by examining blood cholesterol levels. The results of the study revealed that NMN supplementation led to a reduction of both total cholesterol and LDL cholesterol levels. These two types of cholesterol are associated with an increased risk of heart-related problems. The findings suggest that NMN has a positive effect on the cardiovascular system by lowering cholesterol levels, contributing to improved cardiovascular health. 

Moreover, the study also examined the effects of NMN on heart function by assessing diastolic and systolic blood pressure. Notably, the results demonstrated that NMN supplementation specifically reduced diastolic blood pressure, which is a crucial factor in hypertension (high blood pressure), while systolic blood pressure remained unaffected. These findings indicate that NMN supplementation holds an approach for mitigating hypertension in overweight and obese adults. By targeting diastolic blood pressure, NMN contributes to the management of this cardiovascular condition. 

Could Longer durations of NMN supplements reverse obesity and metabolic dysfunction?

The study presents compelling evidence supporting the effectiveness of NMN in reducing body weight among overweight or obese adults. However, the study’s relatively short duration raises questions about the potential long-term anti-obesity benefits that could be achieved with a more extended dosing regimen. It is reasonable to speculate that a longer study period could enhance the anti-obesity effects of NMN. Furthermore, extending the duration of the study may lead to greater reductions in cholesterol and blood pressure levels. 

It is essential to acknowledge that the study had a limited number of participants (21 individuals) who received NMN, and no effects on muscle strength or recovery time were observed in this particular study. Conducting future research with a larger sample size and longer duration could explore the possibility of NMN improving muscle performance when combined with a workout regimen. 

In summary, the findings of this study offer scientific insights for overweight and obese adults seeking weight loss options and considering NMN supplementation. 



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